KLHL31, also known as kelch-like protein 31, BTB and kelch domain-containing protein 6, kelch-like protein KLHL or kelch repeat and BTB domain-containing protein 1, is a 634 amino acid protein similar to the Drosophila kelch protein. KLHL31 is expressed strongly in skeletal muscle and weakly in heart. KLHL31 contains one BACK (BTB/kelch associated) domain, which may indicate a role in substrate orientation in E3 ligase complexes. KLHL31 also contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
recommended for detection of KLHL31 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: