| Product Name | AMDHD1 Antibody (D-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of AMDHD1 of human origin |
| Modification Notes | AMDHD1 (amidohydrolase domain containing 1), also known as probable imidazolonepropionase, is a 426 amino acid protein belonging to the hutI family. AMDHD1 participates in hydrolase activity, acting on carbon-nitrogen bonds, but not peptide bonds, in cyclic amides. AMDHD1 also functions in imidazolonepropionase activity and metal ion binding, whereby binding one iron or zinc ion per subunit. AMDHD1 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up approximately 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, characterized by heart and facial developmental defects, is caused by a mutant form of the PTPN11 gene product, SH-PTP2. Chromosome 12 is also linked to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster that encodes C-type lectin proteins, which mediate the NK cell response to MHC I interaction. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of AMDHD1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with AMDHD2 also reactive with additional species, including canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of AMDHD1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of AMDHD1 of human origin |
| Entrez Gene | 144193 |
|---|
| Application Notes | recommended for detection of AMDHD1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with AMDHD2 also reactive with additional species, including canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
