epitope corresponding to amino acids 1-300 mapping at the N-terminus of DET1 of human origin
Modification Notes
DET1 (de-etiolated homolog 1), is a 550 amino acid highly conserved nuclear protein that is expressed in the ovary, some lymphoid organs and resting leukocytes. DET1 is a component of the E3 ubiquitin ligase Doublecortin DET1-COP1 complex, which is required for ubiquitination and degradation of proto-oncogenic transcription factor c-Jun. DET1 enhances the activity of several members of the UBC (Ub-conjugating enzyme) family and modulates Cul-4A functions. DET1 is involved in multiple plant developmental processes and acts as an essential negative regulator of photomorphogenesis.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of DET1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-300 mapping at the N-terminus of DET1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-300 mapping at the N-terminus of DET1 of human origin
recommended for detection of DET1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.