| Product Name | SLC6A2 Antibody (H-67) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 551-617 mapping within a C-terminal cytoplasmic domain of SLC6A2 of human origin |
| Modification Notes | The norepinephrine transporter encoded by SLC6A2 is a multi-pass membrane protein that terminates noradrenergic signaling by rapid re-uptake of neuronally released norepinephrine (NE) into presynaptic terminals. It belongs to the sodium: neurotransmitter symporter (SNF) family and interacts with PRKCABP. The norepinephrine transporter regulates NE-mediated behavioral and physiological effects, including mood, depression, feeding behavior, cognition, regulation of blood pressure and heart rate. Consequently, the norepinephrine transporter is the target of several drugs used in the treatment or diagnosis of disorders, including depression, attention-deficit hyperactivity disorder and feeding disturbances. Defects in SLC6A2, the gene encoding the norepinephrine transporter, can cause orthostatic intolerance, a syndrome that is associated with postural tachycardia and is characterized by lightheadedness, fatigue, altered mentation and syncope. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SLC6A2 (also known as Norepinephrine Transporter) of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 551-617 mapping within a C-terminal cytoplasmic domain of SLC6A2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 551-617 mapping within a C-terminal cytoplasmic domain of SLC6A2 of human origin |
| Entrez Gene | 6530 |
|---|
| Application Notes | recommended for detection of SLC6A2 (also known as Norepinephrine Transporter) of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
