Application
Western blot analysis of Transcobalamin II expression in non-transfected: (A) and human Transcobalamin II transfected: (B) 293 whole cell lysates.| Product Name | Transcobalamin II Antibody (H-260) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 168-427 mapping at the C-terminus of Transcobalamin II of human origin |
| Modification Notes | Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of precursor and mature Transcobalamin II of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 168-427 mapping at the C-terminus of Transcobalamin II of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 168-427 mapping at the C-terminus of Transcobalamin II of human origin |
| Entrez Gene | 6948 |
|---|
Application
Western blot analysis of Transcobalamin II expression in non-transfected: (A) and human Transcobalamin II transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of precursor and mature Transcobalamin II of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
