| Product Name | GITRL Antibody (FL-177) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-177 representing full length GITRL of human origin |
| Modification Notes | GITRL (glucocorticoid-induced TNF-related ligand), a polypeptide encoded by a human umbilical endothelial cell cDNA, is a member of the TNF (tumor necrosis factor) superfamily. GITRL has a type 2 transmembrane topology that is characteristic of the TNF family. The TNF superfamilies regulate diverse biological functions, including cell proliferation, differentiation and survival. GITRL is found on vascular endothelial cells and in several peripheral tissues (small intestine, ovary, testis and kidney), where it may modulate T lymphocyte survival. The GITR receptor recognizes GITRL and the two interact to regulate NF˚B activation. The ligand-receptor pair of GITRL-GITR protects cells against AICD (activation-induced cell death). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GITRL of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-177 representing full length GITRL of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-177 representing full length GITRL of human origin |
| Entrez Gene | 8995 |
|---|
| Application Notes | recommended for detection of GITRL of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
