| Product Name | ADAM5 Antibody (R-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 501-620 mapping near the C-terminus of ADAM5 of rat origin |
| Modification Notes | ADAMs (disintegrin and metalloproteinase domain), also known as MDCs (metalloproteinase, disintegrin and cysteine-rich domain) or cellular disintegrins, are a family of proteins that are ubiquitously expressed. They catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAMs are membrane-anchored, glycosylated, Zn2+ dependent proteases, and there are over 30 different members in the family, with many diverse functions. ADAM1-6 localize to the testis, are developmentally regulated and are involved in spermatogenesis and sperm-egg binding and fusion. ADAM5 is expressed on the sperm surface. The ADAM5 precursor originates in the testis and is processed during epididymal maturation. Evidence suggests that ADAM5 plays a critical role in fertilization through a significant expressional relationship with ADAM 2 and 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ADAM5 of rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 501-620 mapping near the C-terminus of ADAM5 of rat origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 501-620 mapping near the C-terminus of ADAM5 of rat origin |
| Application Notes | recommended for detection of ADAM5 of rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
