Application
Western blot analysis of pirin expression in HeLa (A), Hep G2 (B), THP-1 (C) and A549 (D) whole cell lysates.| Product Name | pirin Antibody (FL-290) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-290 representing full length pirin of human origin |
| Modification Notes | Pirin (also designated iron-binding nuclear protein) is a highly conserved eukaryotic protein involved in transcriptional activation and apoptosis. Pirin mRNA is poorly expressed in all human tissues, and multiple pirin transcripts are expressed in heart and skeletal muscle. Research indicates that the expression of pirin may be localized to subnuclear structures. The interaction of pirin with NFI/CTF1 (nuclear factor I/CCAAT box transcription factor) classifies pirin as a putative NFI/CTF1 cofactor, which might lead to new insights in NFI/CTF1 activity. Pirin may be a significant factor in transcriptional regulation and is presumably involved in the regulation of DNA transcription and replication. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of pirin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-290 representing full length pirin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-290 representing full length pirin of human origin |
| Entrez Gene | 8544 |
|---|
Application
Western blot analysis of pirin expression in HeLa (A), Hep G2 (B), THP-1 (C) and A549 (D) whole cell lysates.| Application Notes | recommended for detection of pirin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
