Application
Western blot analysis of human recombinant KLRG1 fusion protein.Application
Immunofluorescence staining of methanol-fixed Jurkat cells showing membrane localization.| Product Name | KLRG1 Antibody (H-85) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-85 of KLRG1 of human origin |
| Modification Notes | Killer cell lectin-like receptor G1 (KLRG1) is expressed as a homodimer, composed of glycosylated 30-38 kDa subunits, on natural killer (NK) cells and activated CD8 T cells. KLRG1 expression is tightly regulated and is induced through different molecular mechanisms in varying subsets of immune-responsive cells. Induction of the receptor leads to inhibition of NK cell-mediated cytotoxicity and cytokine production, indicating a role for KLRG1 in the termination of NK cell activation. A rat homologue of KLRG1, designated mast cell function-associated antigen (MAFA), was originally islolated from the RBL-2H3 cell line. MAFA is expressed in rat mast cells and basophils. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KLRG1 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-85 of KLRG1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-85 of KLRG1 of human origin |
| Entrez Gene | 10219 |
|---|
Application
Western blot analysis of human recombinant KLRG1 fusion protein.
Application
Immunofluorescence staining of methanol-fixed Jurkat cells showing membrane localization.| Application Notes | recommended for detection of KLRG1 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
