Application
Western blot analysis of KIF12 expression in Mia PaCa-2 whole cell lysate.| Product Name | KIF12 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 347-646 mapping at the C-terminus of KIF12 of human origin |
| Modification Notes | Kinesin is a cytoskeletal motor protein involved in axonal transport and cell division. The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination, and speed of transportation of a variety of important functional molecules, including mRNA. KIFs are involved in neuronal function and development. Kinesin family member 12 (KIF12) is a kinesin-like 651-amino-acid protein which is involved in mitotically linked cytokinesis. KIF12 is required during mitosis for normal myosin II localization and during late anaphase and telophase for normal nuclear separation. The KIF12 gene consists of a KISc domain, a coiled-coil domain with an internal hinge region and a C-terminal tail domain. KIF12 mRNA is expressed in fetal liver, adult brain, pancreatic islet, kidney tumors, and uterine and pancreatic cancers. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KIF12 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 347-646 mapping at the C-terminus of KIF12 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 347-646 mapping at the C-terminus of KIF12 of human origin |
| Entrez Gene | 113220 |
|---|
Application
Western blot analysis of KIF12 expression in Mia PaCa-2 whole cell lysate.| Application Notes | recommended for detection of KIF12 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
