| Product Name | Transaldolase Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Transaldolase of human origin |
| Modification Notes | Proper cell growth, differentiation and survival relies on a series of enzymes involved in complex redox and metabolic pathways. One of these enzymes, Transaldolase, contributes to the generation of NADPH in the nonoxidative phase of the pentose phosphate pathway (PPP) and is important for maintaining metabolite balance. In conjunction with several other enzymes, Transaldolase works to maintain the mitochondrial transmembrane potential by producing both ribose-5-phosphate and NADPH for use in nucleic acid and lipid biosynthesis. The role of Transaldolase in the PPP of spermatoza is of significant importance, as deficiencies in Transaldolase are directly related with male infertility due to loss of sperm structure and function. Mutations in the gene encoding Transaldolase are thought to play a role in multiple sclerosis and are the direct cause of hepatosplenomegaly and telangiectases of the skin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Transaldolase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Transaldolase of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Transaldolase of human origin |
| Entrez Gene | 6888 |
|---|
| Application Notes | recommended for detection of Transaldolase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
