| Product Name | KIR6.2 Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 336-390 mapping at the C-terminus of KIR6.2 of human origin |
| Modification Notes | ATP-sensitive K+ channels play important roles in many cellular functions by coupling cell metabolism to electrical activity. KIR6.1 and KIR6.2 are members of the KIR (for inwardly rectifying potassium channel) family of potassium channels. Inward rectifying K+ channels possess a greater tendency to allow potasium to flow into the cell rather than out of it. These channels comprise two subunits: a KIR6.0 subfamily component and a SUR component, which is a member of the ATP-binding cassette protein superfamily. Mutations in the gene coding for these channels are a cause of an autosomal recessive disorder characterized by unregulated insulin secretion. The amino-terminal and carboxyl-terminal domains of KIR channel subunits are both intracellular, and the two intracellular domains of KIR6.2 physically interact with each other. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KIR6.2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 336-390 mapping at the C-terminus of KIR6.2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 336-390 mapping at the C-terminus of KIR6.2 of human origin |
| Entrez Gene | 3767 |
|---|
| Application Notes | recommended for detection of KIR6.2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
