| Product Name | Spir-1 Antibody (F-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of Spir-1 of human origin |
| Modification Notes | Spir-1 (spire homolog 1) is a 756 amino acid protein that localizes to the cytoskeleton, as well as to the perinuclear region of the cytoplasm, and contains one KIND domain and two WH2 domains. Functioning as an Actin nucleation factor, Spir-1 assists in new filament growth and is involved in vesicle transport processes, effectively providing a link between intracellular transport and Actin organization. Multiple isoforms of Spir-1 exist due to alternative splicing events. The gene encoding Spir-1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Spir-1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Spir-1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Spir-1 of human origin |
| Entrez Gene | 56907 |
|---|
| Application Notes | recommended for detection of Spir-1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
