| Product Name | CaSR Antibody (H-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 111-210 mapping within an N-terminal extracellular domain of CaSR of human origin |
| Modification Notes | Extracellular calcium-sensing receptor (CaSR), also designated parathyroid cell calcium-sensing receptor, is an integral membrane protein that belongs to the G protein-coupled receptor 3 family. CaSR is involved in maintaining a stable calcium concentration by acting as an sensor of the extracellular calcium levels for the parathyroid and kidney. Its activity is mediated by a G protein which activates a phosphatidylinositol-calcium second messenger system. Defects that activate CaSR cause autosomal dominant hypocalcemia, whereas mutations that inactivate the protein cause familial hypocalciuric hypercalcemia. CaSR is expressed mainly in kidney, and is also expressed in intestine, placenta and brain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Extracellular calcium-sensing receptor of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 111-210 mapping within an N-terminal extracellular domain of CaSR of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 111-210 mapping within an N-terminal extracellular domain of CaSR of human origin |
| Entrez Gene | 846 |
|---|
| Application Notes | recommended for detection of Extracellular calcium-sensing receptor of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
