| Product Name | NSUN5 Antibody (H-139) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 227-365 mapping near the C-terminus of NSUN5 of human origin |
| Modification Notes | NSUN5 (NOL1/NOP2/Sun domain family, member 5), also known as NOL1, p120 or NOL1R, is a 429 amino acid protein that belongs to the methyltransferase superfamily and exists as multiple alternatively spliced isoforms. Expressed ubiquitously with higher expression in heart, placenta and skeletal muscle, NSUN5 is thought to function as an S-adenosyl-L-methionine-dependent methyl-transferase whose absence may be associated with the pathogenesis of Williams syndrome. NSUN5 is subject to post-translational phosphorylation, probably by ATM or ATR. The gene encoding NSUN5 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NSUN5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 227-365 mapping near the C-terminus of NSUN5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 227-365 mapping near the C-terminus of NSUN5 of human origin |
| Entrez Gene | 55695 |
|---|
| Application Notes | recommended for detection of NSUN5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
