Application
Western blot analysis of NDUFB11 expression in mouse skeletal muscle (A), mouse kidney (B) and rat heart (C) tissue extracts.Application
Western blot analysis of NDUFB11 expression in Hep G2 (A), HeLa (B), Jurkat (C), K-562 (D) and Ramos (E) whole cell lysates.| Product Name | NDUFB11 Antibody (FL-153) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-153 representing full length NDUFB11 of human origin |
| Modification Notes | Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NDUFB11 of human, equine, canine, bovine and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-153 representing full length NDUFB11 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-153 representing full length NDUFB11 of human origin |
| Entrez Gene | 54539 |
|---|
Application
Western blot analysis of NDUFB11 expression in mouse skeletal muscle (A), mouse kidney (B) and rat heart (C) tissue extracts.
Application
Western blot analysis of NDUFB11 expression in Hep G2 (A), HeLa (B), Jurkat (C), K-562 (D) and Ramos (E) whole cell lysates.| Application Notes | recommended for detection of NDUFB11 of human, equine, canine, bovine and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
