Application
Western blot analysis of glycosylated Opalin expression in rat cerebellum tissue extract.Application
Western blot analysis of Opalin expression in mouse brain tissue extract.| Product Name | Opalin Antibody (FL-143) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-143 representing full length Opalin of mouse origin |
| Modification Notes | Opalin, also known as HTMP10, oligodendrocytic myelin paranodal and inner loop protein or TMEM10 (transmembrane protein 10), is a 141 amino acid single-pass type I membrane protein that is expressed specifically in oligodendrocytes of brain. The gene encoding Opalin maps to human chromosome 10q24.1.Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Opalin of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-143 representing full length Opalin of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-143 representing full length Opalin of mouse origin |
| Entrez Gene | 93377 |
|---|
Application
Western blot analysis of glycosylated Opalin expression in rat cerebellum tissue extract.
Application
Western blot analysis of Opalin expression in mouse brain tissue extract.| Application Notes | recommended for detection of Opalin of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
