| Product Name | HIPK1 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 31-80 mapping near the N-terminus of HIPK1 of human origin |
| Modification Notes | The Homeodomain-Interacting Protein Kinase (HIPK) family, which includes HIPK1, HIPK2 and HIPK3, are evolutionarily conserved nuclear serine/threonine kinases that interact with homeoproteins. The HIPK family of proteins act as transcriptional regulators, chromatin modifiers, cytoplasmic signal transducers, transmembrane proteins, and the E2 component of SUMO ligase. HIPK1 is a 1210 amino acid protein that is ubiquitously expressed with highest levels in skeletal muscle and heart. HIPK1 may play a role as a corepressor for homeodomain transcription factors and may phosphorylate Daxx in response to stress. It is suggested that HIPK1 may be involved in malignant squamous cell tumor formation. Four isoforms exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HIPK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 31-80 mapping near the N-terminus of HIPK1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 31-80 mapping near the N-terminus of HIPK1 of human origin |
| Entrez Gene | 204851 |
|---|
| Application Notes | recommended for detection of HIPK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
