| Product Name | galectin-5/9 Antibody (R-145) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-145 representing full length galectin-5 of rat origin |
| Modification Notes | Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-9, also known as Ecalectin, Gal-9, hUAT2, HOM-HD-21 or LGALS9, maps to human chromosome 17. Galectin-9 is an integral membrane protein that exists as two isoforms, a long form and a short form, which differ by an internal stretch of 32 amino acids. Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes that is expressed in organs of the gastrointestinal tract, aorta, liver, kidney, liver, pancreatic islets, lung, tonsil and some colorectal carcinoma, and in the cell lines HUVEC, U-937, HL60, HeLa and Jurkat. Introduction of IL-1beta enhances Galectin-9 expression. Increased expression of Galectin-9 induces apoptosis in thymocytes and CD8+ cells. Galectin-9 is involved in immuno/inflammation processes in potential-sensitive uric acid translocation and contributes to inflammatory reactions in the central nervous system (CNS). Galectin-5, also known as RL-18, may function in erythrocyte differentiation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of galectin-5 and galectin-9 of rat origin and, to a lesser extent, galectin-9 of mouse origin byy WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-145 representing full length galectin-5 of rat origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-145 representing full length galectin-5 of rat origin |
| Entrez Gene | 16859 |
|---|
| Application Notes | recommended for detection of galectin-5 and galectin-9 of rat origin and, to a lesser extent, galectin-9 of mouse origin byy WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
