Application
Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.| Product Name | LTβR Antibody (M-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 41-150 mapping near the N-terminus of LTβR of mouse origin |
| Modification Notes | Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen, CD40 and lymphotoxin ∫ receptor (LT∫R). LT∫R is activated upon association with the heterotrimeric lymphotoxin LT-å1/∫2, resulting in NFkB activation and the initiation of apoptosis. LT∫R is expressed on the surface of most cell types, excluding T and B lymphocytes, and it is involved in lymphoid organ development . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LTβR of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 41-150 mapping near the N-terminus of LT&beta R of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 41-150 mapping near the N-terminus of LTβR of mouse origin |
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.| Application Notes | recommended for detection of LTβR of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
