Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.Application
Western blot analysis of ASS1 expression in non-transfected: (A) and mouse ASS1 transfected: (B) 293T whole cell lysates.| Product Name | ASS1 Antibody (H-231) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-231 mapping at the N-terminus of ASS1 of human origin |
| Modification Notes | ASS1, also known as argininosuccinate synthase or citrulline-aspartate ligase, belongs to the argininosuccinate synthase family. ASS1 is an urea cycle enzyme with a tetrameric structure composed of identical subunits. It is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Argininosuccinate synthase (ASS1) of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-231 mapping at the N-terminus of ASS1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-231 mapping at the N-terminus of ASS1 of human origin |
| Entrez Gene | 445 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.
Application
Western blot analysis of ASS1 expression in non-transfected: (A) and mouse ASS1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Argininosuccinate synthase (ASS1) of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
