| Product Name | TNK1 Antibody (H-53) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 147-199 mapping near the N-terminus of TNK1 of human origin |
| Modification Notes | TNK1 is a 666 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one SH3 domain and one protein kinase domain. Expressed at high levels in fetal lung, liver, brain and kidney and at lower levels in adult ovary, colon, prostate and testis, TNK1 functions to catalyze the ATP-dependent conversion of an L-tyrosine protein to a phosphorylated L-tyrosine protein and is thought to be involved in the negative regulation of cell growth, possibly playing a role in tumor suppression. Additionally, TNK1 may be associated with phospholipid signal transduction and fetal development pathways, further suggesting an important role in growth and development. Multiple isoforms of TNK1 exist and are encoded by a gene which maps to human chromosome 17. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TNK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 147-199 mapping near the N-terminus of TNK1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 147-199 mapping near the N-terminus of TNK1 of human origin |
| Entrez Gene | 8711 |
|---|
| Application Notes | recommended for detection of TNK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
