| Product Name | ADNP Antibody (H-138) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-138 mapping at the N-terminus of ADNP of human origin |
| Modification Notes | Activity-dependent neuroprotector (ADNP), also designated activity-dependent neuroprotective protein, is a nuclear protein that functions as a putative transcription factor and may participate in normal growth and cancer proliferation. ADNP is a highly conserved vasoactive intestinal peptide (VIP) responsive gene that is expressed profusely in the brain (primarily cerebellum and cortex regions) and is crucial for brain formation and embryonic development. ADNP is also highly expressed in kidney, placenta, heart, skeletal muscle, breast, and colon cancer tissues. Studies indicate that neuroprotection by subpicomolar PACAP38 might be mediated partially by expression of ADNP. A correlation between brain injuries and elevated ADNP levels indicates a potential involvement of ADNP in an endogenous compensatory mechanism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ADNP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-138 mapping at the N-terminus of ADNP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-138 mapping at the N-terminus of ADNP of human origin |
| Entrez Gene | 23394 |
|---|
| Application Notes | recommended for detection of ADNP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
