| Product Name | Sucrase-Isomaltase Antibody (H-123) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 839-961 mapping within an internal region of Sucrase-Isomaltase of human origin |
| Modification Notes | Sucrase-Isomaltase (SI) is a type II brush border membrane protein that plays an important role in the final stage of carbohydrate digestion. Sucrase-Isomaltase is a disaccharidase that catalyzes the hydrolysis of dietary sucrose and maltose and other products of starch digestion. The high degree of amino acid homology between isomaltase and sucrose indicate that the Sucrase-Isomaltase protein was evolved by partial gene duplication. The Sucrase-Isomaltase precursor is proteolytically cleaved when exposed to pancreatic proteases in the intestinal lumen and localizes to the apical membrane of adult intestinal enterocytes along the intestinal crypt-villus axis. Sucrase-Isomaltase protein deficiency results in osmotic diarrhea due to an inability to hydrolyze intestinal disaccharides into component monosaccharides. Congenital Sucrase-Isomaltase deficiency (CSID) is an autosomal recessive human disorder characterized by reduced activities of Sucrase-Isomaltase |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Sucrase-Isomaltase of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 839-961 mapping within an internal region of Sucrase-Isomaltase of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 839-961 mapping within an internal region of Sucrase-Isomaltase of human origin |
| Application Notes | recommended for detection of Sucrase-Isomaltase of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
