Application
Western blot analysis of CD35 expression in TF-1 whole cell lysate.Application
Western blot analysis of CD35 expression in HeLa whole cell lysate.| Product Name | CD35 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1740-2039 mapping at the C-terminus of CD35 of human origin |
| Modification Notes | CD35, also called complement receptor 1 (CR1), functions as the receptor for complement components C3b and C4b, and it mediates the phagocytosis by neutrophils and monocytes of particles coated with C3b or C4b. CD35 is expressed on granulocytes, monocytes, B cells, some NK cells and erythrocytes. CD35 is implicated in systemic lupus erythematosus (SLE), a chronic systemic autoimmune disease characterized by the production of a broad spectrum of autoantibodies against nuclear, cytoplasmic, and cell surface antigens and an overload of the immune complex. There is an increased proteolytic cleavage of leukocyte cell surface CD35 in SLE patients. Sequence analysis suggests that Crry may be the mouse genetic homolog of the CD35 antigen encoded by the human gene CR1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CD35 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1740-2039 mapping at the C-terminus of CD35 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1740-2039 mapping at the C-terminus of CD35 of human origin |
| Entrez Gene | 1378 |
|---|
Application
Western blot analysis of CD35 expression in TF-1 whole cell lysate.
Application
Western blot analysis of CD35 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of CD35 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
