| Product Name | SSTR2 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 320-369 mapping at the C-terminus of SSTR2a of human origin |
| Modification Notes | SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST) (1). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28 (1). SSTR2 gives rise to spliced variants, SSTR2A and 2B (1). SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins (1-3). Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4) (1). Individual target cells typically express more than one SSTR subtype and often all five isoforms (4,5). Subtypes of SSTR can form functional homo- and heterodimers (6,7). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SSTR2a and , to a lesser extent, SSTR2b of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 320-369 mapping at the C-terminus of SSTR2a of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 320-369 mapping at the C-terminus of SSTR2a of human origin |
| Entrez Gene | 6752 |
|---|
| Application Notes | recommended for detection of SSTR2a and , to a lesser extent, SSTR2b of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
