Application
Western blot analysis of SAP 97 expression in SKBR-3 whole cell lysate.Application
Western blot analysis of SAP 97 expression in MCF7 (A) and SK-N-SH (B) whole cell lysates.| Product Name | SAP 97 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 49-108 mapping at the N-terminus of SAP 97 of human origin |
| Modification Notes | The discs large (dlg) tumor suppressor gene was first identified in Drosophila through genetic analysis of germline mutations. Several mammalian homologs were subsequently identified and categorized into a protein family designated MAGUK (membrane-associated guanylate kinase homolog). The mammalian homolog of dlg, SAP 97, is also known as hdlg-1 (human) and NE-dlg (neuronal and endocrine). The rat synaptic protein SAP 90 (also designated PSD-95) also shares homology with these proteins. MAGUKs are localized at the membrane-cytoskeleton interface and contain several distinct domains which suggest a role for these proteins in intracellular signal transduction. Interaction of hdlg-1 and NE-dlg with the tumor suppresor protein APC suggest that MAGUK proteins may also play a role in regulation of growth. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SAP 97 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 49-108 mapping at the N-terminus of SAP 97 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 49-108 mapping at the N-terminus of SAP 97 of human origin |
| Entrez Gene | 1739 |
|---|
Application
Western blot analysis of SAP 97 expression in SKBR-3 whole cell lysate.
Application
Western blot analysis of SAP 97 expression in MCF7 (A) and SK-N-SH (B) whole cell lysates.| Application Notes | recommended for detection of SAP 97 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
