epitope corresponding to amino acids 1-300 mapping at the N-terminus of IVNS1ABP of human origin
Modification Notes
IVNS1ABP (influenza virus NS1A binding protein), also known as ARA3, FLARA3, KIAA0850, NS1 or NS1BP, is a 642 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BACK domain, one BTB (POZ) domain and six Kelch repeats. Functioning as a homodimer that is connected via its BTB domain, IVNS1ABP associates with F-Actin and, via this association, plays an important role in the organization and stabilization of the Actin skeleton. Due to its role in cytoskeletal function, IVNS1ABP participates in a variety of events throughout the cell, including the regulation of cell division and pre-mRNA splicing, the activation of the ERK signaling pathway and the protection of neurons from dendritic spines.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of IVNS1ABP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-300 mapping at the N-terminus of IVNS1ABP of human origin
Tissue Specificity
epitope corresponding to amino acids 1-300 mapping at the N-terminus of IVNS1ABP of human origin
Western blot analysis of IVNS1ABP expression in HeLa nuclear extract.
Application Notes
recommended for detection of IVNS1ABP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.