Application
Western blot analysis of TH-POK expression in non-transfected: (A) and mouse TH-POK transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TH-POK expression in non-transfected: (A) and mouse TH-POK transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TH-POK expression in non-transfected: (A) and human TH-POK transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TH-POK expression in 293 whole cell lysate.Application
Western blot analysis of TH-POK expression in non-transfected: (A) and human TH-POK transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TH-POK expression in non-transfected: (A) and human TH-POK transfected: (B) 293T whole cell lysates.| Product Name | TH-POK Antibody (B-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TH-POK of mouse and human origin by WB, IP and ELISA |
| Modification Notes | TH-POK (T-helper-inducing POZ/Krueppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or krueppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and fibronectin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TH-POK of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TH-POK of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 51043 |
|---|
Application
Western blot analysis of TH-POK expression in non-transfected: (A) and mouse TH-POK transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TH-POK expression in non-transfected: (A) and mouse TH-POK transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TH-POK expression in non-transfected: (A) and human TH-POK transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TH-POK expression in 293 whole cell lysate.
Application
Western blot analysis of TH-POK expression in non-transfected: (A) and human TH-POK transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TH-POK expression in non-transfected: (A) and human TH-POK transfected: (B) 293T whole cell lysates.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
