Application
Western blot analysis of SR-1D expression in 293T (A), HeLa (B), CCRF-CEM (C) and ES-2 (D) whole cell lysates and mouse brain tissue extract (E).Application
Western blot analysis of SR-1D expression in T98G (A), SH-SY5Y (B) and EOC 13.31 (C) whole cell lysates and mouse brain tissue extract (D).Application
Western blot analysis of SR-1D expression in rat brain tissue extract.| Product Name | SR-1D Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 221-290 mapping to an internal region of SR-1D of human origin |
| Modification Notes | The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SR-1D of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 221-290 mapping to an internal region of SR-1D of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 221-290 mapping to an internal region of SR-1D of human origin |
| Entrez Gene | 3352 |
|---|
Application
Western blot analysis of SR-1D expression in 293T (A), HeLa (B), CCRF-CEM (C) and ES-2 (D) whole cell lysates and mouse brain tissue extract (E).
Application
Western blot analysis of SR-1D expression in T98G (A), SH-SY5Y (B) and EOC 13.31 (C) whole cell lysates and mouse brain tissue extract (D).
Application
Western blot analysis of SR-1D expression in rat brain tissue extract.| Application Notes | recommended for detection of SR-1D of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
