Application
Western blot analysis of KOR-3 expression in Raji (A), C6 (B) and SK-N-MC (C) whole cell lysates.| Product Name | KOR-3 Antibody (H-85) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 161-245 mapping to an internal region of kappa-type opioid receptor-3 (KOR-3) of human origin |
| Modification Notes | Endogenous opioid peptides and opiates like morphine mediate their cellular effects through membrane bound receptors. Three different types of opioid receptors have been identified, mu-type, delta-type and kappa-type. A fourth opioid receptor, KOR-3 (kappa-type opioid receptor, also designated ORL1- Opioid Receptor Like 1), has been identified. Though closely related genetically to the other opioid receptors, KOR-3 has a distinct pharmacological profile. Nociceptin, the neuropeptide which activates KOR-3, is structurally similar to the kappa-opioid peptide dynorphin A, but quite different in its mode of interaction with its receptor. KOR-3 is widely expressed in the nervous system, and is likely to modulate a broad range of physiological and behavioral functions. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KOR-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 161-245 mapping to an internal region of kappa-type opioid receptor-3 (KOR-3) of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 161-245 mapping to an internal region of kappa-type opioid receptor-3 (KOR-3) of human origin |
| Entrez Gene | 4987 |
|---|
Application
Western blot analysis of KOR-3 expression in Raji (A), C6 (B) and SK-N-MC (C) whole cell lysates.| Application Notes | recommended for detection of KOR-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
