| Product Name | UQCRB Antibody (E-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of UQCRB of human origin |
| Modification Notes | UQCRB (ubiquinol-cytochrome c reductase binding protein), also known as complex III subunit VII, ubiquinol-cytochrome c reductase complex 14 kDa protein and QCR7, is a 111 amino acid mitochondrion inner membrane protein. UQCRB is a component of the ubiquinol-cytochrome c reductase complex, also known as complex III or cytochrome b-c1 complex, which is a constituent of the mitochondrial respiratory chain. The ubiquinol-cytochrome c reductase complex is composed of two core proteins (UQCRC1 and UQCRC2), three respiratory subunits (cytochrome c1, cytochrome b and Rieske) and six low-molecular weight proteins (UQCRH, UQCRB, QP-C, UQCR10, UQCR11 and a cleavage product of Rieske). UQCRB binds ubiquinone and is involved in the transfer of electrons across the mitochondrion inner membrane. Mutations in the gene that encodes UQCRB have been linked to mitochondrial complex III deficiency (CIII deficiency), a condition characterized by congenital lactic acidosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of UQCRB and LOC727947 of human origin by WB, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of UQCRB of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of UQCRB of human origin |
| Application Notes | recommended for detection of UQCRB and LOC727947 of human origin by WB, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
