Application
Western blot analysis of RBM9 expression in non-transfected: (A) and human RBM9 transfected: (B) 293T whole cell lysates.| Product Name | RBM9 Antibody (H-75) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 46-120 mapping near the N-terminus of RBM9 of human origin |
| Modification Notes | RBM9 (RNA binding motif protein 9), also known as RTA, fxh, FOX2, Fox-2, HNRBP2 or HRNBP2, is a 390 amino acid protein that contains one RRM (RNA recognition motif) domain. RBM9 is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. RBM9 regulates the splicing activity of the highly conserved RNA 5'-UGCAUGU-3' element, an intron splicing enhancer that is often located adjacent to tissue-specific alternative exons. RBM9 prevents binding of U2AF65 (U2 snRNP auxiliary factor large subunit) to the 3' splice site of the RNA splicing element which affects alternative splicing of tissue-specific exons. RBM9 also interacts with the ERa (estrogen receptor alpha) transcription factor and regulates ERa transcriptional activity. Eight isoforms of RBM9 exists due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RBM9 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other RBM family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 46-120 mapping near the N-terminus of RBM9 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 46-120 mapping near the N-terminus of RBM9 of human origin |
| Entrez Gene | 23543 |
|---|
Application
Western blot analysis of RBM9 expression in non-transfected: (A) and human RBM9 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of RBM9 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other RBM family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
