recommended for detection of NHE-9 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA
Modification Notes
NHE-9 (Na(+)/H(+) exchanger 9), also known as SLC9A9 (solute carrier family 9 (sodium/hydrogen exchanger), member 9), is a 645 amino acid multi-pass membrane protein that localizes to late endosomes and belongs to the monovalent cation/proton antiporter family of ion transporters. Expressed ubiquitously with highest levels present in heart and skeletal muscle and lower levels present in liver, placenta and kidney, NHE-9 is thought to play a role in the electroneutral exchange of sodium ions for proteins across membrane and, via this activity, is involved in the maintenance of organelle ion homeostasis. Chromosomal aberrations in the NHE-9 gene are associated with the pathogenesis of early-onset behavioral/developmental disorder with features of attention deficit-hyperactivity disorder and intellectual disability (ADHD).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of NHE-9 of mouse and human origin by WB IP IF IHC(P) and ELISA
Tissue Specificity
recommended for detection of NHE-9 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA