Application
Western blot analysis of MRI1 expression in non-transfected: (A) and mouse MRI1 transfected: (B) 293T whole cell lysates.| Product Name | MRI1 Antibody (A-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against synthetic MRI1 peptide of mouse origin |
| Modification Notes | MRI1 (methylthioribose-1-phosphate isomerase), also known as MTR-1-P isomerase, is a 369 amino acid enzyme belonging to the eIF2B alpha/beta/delta subunit family. MRI1 is involved in the amino-acid biosynthesis pathway, specifically the L-methionine biosynthesis via salvage pathway. MRI1 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). MRI1 is expressed as two isoforms produced by alternative splicing. The gene that encodes MRI1 maps to human chromosome 19, which consists of around 63 million bases with over 1,400 genes. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcå receptors. Key genes for eye color and hair color also map to chromosome 19. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of MRI1 of mouse origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against synthetic MRI1 peptide of mouse origin |
|---|---|
| Tissue Specificity | raised against synthetic MRI1 peptide of mouse origin |
| Entrez Gene | 67873 |
|---|
Application
Western blot analysis of MRI1 expression in non-transfected: (A) and mouse MRI1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of MRI1 of mouse origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
