| Product Name | SGLT-6 Antibody (D-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of SGLT-6 of human origin and Slc5a11 of mouse and rat origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Modification Notes | SGLT-6, also known as SLC5A11 (solute carrier family 5 (sodium/glucose co-transporter), member 11) KST1, SLGTX or SMIT2, is a 675 amino acid multi-pass membrane protein that belongs to the sodium/solute symporter family of transport proteins. Expressed at high levels in kidney, heart, placenta, liver and skeletal muscle, SGLT-6 is involved in the co-transport of Myo-inositol with sodium, specifically facilitating the transport of two Myo-inositols per sodium ion. In addition to its role in sodium transport, SGLT-6 also participates in the transport of glucose and xylose and may function to induce Pdcd-1-dependent cell apoptosis. The gene encoding SGLT-6 is an autoimmune modifier in systemic lupus erythematosus (SLE), suggesting an involvement for SGLT-6 in the pathogenesis of SLE. Multiple isoforms of SGLT-6 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of SGLT-6 of human origin and Slc5a11 of mouse and rat origin by WB IP and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of SGLT-6 of human origin and Slc5a11 of mouse and rat origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 115584 |
|---|
| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
