epitope corresponding to amino acids 1251-1550 mapping within a C-terminal cytoplasmic domain of LTRPC7 of human origin
Modification Notes
Transient receptor potential (TRPC) ion channels are a super-family of six transmembrane segment-spanning, gated cation channels. TRPC subtypes mediate store-operated Ca2+ entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. Trp ion channels influence calcium-depletion-induced calcium influx processes in response to chemo-, mechano- and osmo-regulatory events. LTRPC7 and LTRPC2 (TRPC7) are both members of the long TRPC subfamily, which is characterized by open reading frames of around 1600 amino-acid residues. LTRPC7 is another divalent cation channel for Ca2+ and Mg2+.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LTRPC7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1251-1550 mapping within a C-terminal cytoplasmic domain of LTRPC7 of human origin
Tissue Specificity
epitope corresponding to amino acids 1251-1550 mapping within a C-terminal cytoplasmic domain of LTRPC7 of human origin
Western blot analysis of LTRPC7 expression in HeLa whole cell lysate.
Application Notes
recommended for detection of LTRPC7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.