epitope mapping within an internal region of FARP1 of human origin
Modification Notes
FARP1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1), also known as PLEKHC2 or CDEP, is a 1,045 amino acid protein that contains one FERM domain, one DH domain and two PH domains. Existing as multiple alternatively spliced isoforms that are expressed in fetal heart, brain and spleen, as well as in adult lung, kidney and testis, FARP1 is thought to function as a Rho-guanine nucleotide exchange factor that may play a role in linking the cell membrane to the cytoskeleton. The gene encoding FARP1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of FARP1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of FARP1 of human origin
Tissue Specificity
epitope mapping within an internal region of FARP1 of human origin
Western blot analysis of FARP1 expression in F9 whole cell lysate.
Application Notes
recommended for detection of FARP1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.