| Product Name | Exportin 7 Antibody (H-82) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 520-594 mapping within an internal region of Exportin 7 of human origin |
| Modification Notes | Exportin 7 is also known as RanBP16 (ran-binding protein 16) or XPO7 and is a 1,087 amino acid protein. Exportin 7 is primarily expressed in testis, thyroid and bone marrow, but is also expressed in lung, liver and small intestine. Exportin 7 translocates proteins and large RNAs through the nuclear pore complex (NPC) and is localized to the cytoplasm and nucleus. Exportin 7 has two types of receptors, designated importins and exportins, both of which recognize proteins that contain nuclear localization signals (NLSs) and are targeted for transport either in or out of the nucleus via the NPC. Additionally, the nucleocytoplasmic RanGTP gradient regulates Exportin 7 distribution, and enables Exportin 7 to bind and release proteins and large RNAs before and after their transportation. Exportin 7 is thought to play a role in erythroid differentiation and may also interact with cancer-associated proteins, suggesting a role for Exportin 7 in tumorigenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Exportin 7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 520-594 mapping within an internal region of Exportin 7 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 520-594 mapping within an internal region of Exportin 7 of human origin |
| Entrez Gene | 23039 |
|---|
| Application Notes | recommended for detection of Exportin 7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
