| Product Name | α1D-AR Antibody (H-142) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 431-572 of α1D adrenergic receptor of human origin |
| Modification Notes | Alpha 1D-adrenergic receptors (å1D-ARs) couple to Gq/11 and participate directly in sympathetic regulation of systemic blood pressure by vasoconstriction. å1D-AR can form hetero-oligomers with å1B receptors. å1D-AR transcripts are abundant in prostate and aorta. å1A adrenergic receptors (å1A-ARs) mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. å1A-adrenergic receptors couple to Gq/11 and regulate blood pressure due to changes in vascular tone and cardiac output. Alternative splicing of this gene generates four isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. å1A-AR transcripts are abundant in heart, brain, liver, and prostate. å1A-AR transcript sizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. å1A-AR transcript sizes of 6.0, 4.0 and 3.0 kb transcripts have been detected in heart, and the 6.0 kb and 4.0 kb transcripts have been detected in prostate. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of α1D adrenergic receptor of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 431-572 of &alpha 1D adrenergic receptor of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 431-572 of α1D adrenergic receptor of human origin |
| Entrez Gene | 146 |
|---|
| Application Notes | recommended for detection of α1D adrenergic receptor of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
