epitope corresponding to amino acids 19-140 representing mature IL-9 of human origin
Modification Notes
Interleukin-9, or IL-9, is a TH2 cytokine that has been shown to promote the antigen-independent growth of some T helper clones. IL-9 is a pleiotropic cytokine with multiple functions on cells of lymphoid, myeloid and mast cell lineages. Both mouse and human cDNAs encode 144 amino acid precursors with 18 amino acid residue signal peptides that are cleaved to form the mature biologically active glycoprotein. Although IL-9 is constitutively expressed in vitro by several transformed T cell lines, IL-9 expression can be induced in human peripheral blood T lymphocytes by T cell activators such as phorbol esters (PHA) and anti-CD3 antibodies. IL-9 exerts its biological effects through the interleukin-9 receptor, IL-9R. IL-9R is composed of at least two subunits: the IL-2 receptor g chain, which is common to the IL-2, IL-4, IL-7 and IL-15 receptors, and one specific to the IL-9 receptor.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of IL-9 of mouse, rat and human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 19-140 representing mature IL-9 of human origin
Tissue Specificity
epitope corresponding to amino acids 19-140 representing mature IL-9 of human origin