Application
Western blot analysis of Prealbumin expression in human plasma tissue extract.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans.Application
Western blot analysis of Prealbumin expression in Hep G2 (A), ARPE-19 (B), H4 (C) and SK-N-MC (D) whole cell lysates and mouse liver (E) and mouse brain (F) tissue extracts.Application
Western blot analysis of human recombinant Prealbumin fusion protein.| Product Name | Prealbumin Antibody (FL-147) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IP,IF,IHC,ELISA |
| recommended for detection of Prealbumin of multiple species, including mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | Human,Mouse,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-147 representing full length Prealbumin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-147 representing full length Prealbumin of human origin |
| Entrez Gene | 7276 |
|---|
Application
Western blot analysis of Prealbumin expression in human plasma tissue extract.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans.
Application
Western blot analysis of Prealbumin expression in Hep G2 (A), ARPE-19 (B), H4 (C) and SK-N-MC (D) whole cell lysates and mouse liver (E) and mouse brain (F) tissue extracts.
Application
Western blot analysis of human recombinant Prealbumin fusion protein.| Application Notes | recommended for detection of Prealbumin of multiple species, including mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
