| Product Name | EF-HB Antibody (S-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of EF-HB of human origin |
| Modification Notes | The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HB (EF-hand domain-containing family member B) is a 831 amino acid protein that contains two EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. There are three isoforms of EF-HB that are produced as a result of alternative splicing events. The gene encoding EF-HB is located on human chromosome three,which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Other well-studied calcium binding proteins that contain EF-hand motifs include calmodulin (CaM), Troponin C, myosin regulatory light chain (MYL) and S-100 proteins. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of EF-HB of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other EF-H family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of EF-HB of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of EF-HB of human origin |
| Entrez Gene | 151651 |
|---|
| Application Notes | recommended for detection of EF-HB of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other EF-H family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
