Application
Western blot analysis of MTP18 expression in non-transfected: (A) and mouse MTP18 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of MTP18 expression in non-transfected: (A) and mouse MTP18 transfected: (B) 293T whole cell lysates.| Product Name | MTP18 Antibody (D-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of MTP18 of human origin |
| Modification Notes | Mitochondria are eukaryotic organelles that convert organic materials into energy in the form of ATP via the process of oxidative phosphorylation. Mitochondria also play important roles in apoptosis, cellular proliferation, regulation of the cellular redox state, heme and steroid synthesis, and glutamate-mediated excitotoxic neuronal injury. A typical cell has hundreds to thousands of mitochondria, each of which contain their own sets of DNA. Mitochondria also have unique proteins that can be used as mitochondrial markers. MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MTP18 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with MTP also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of MTP18 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of MTP18 of human origin |
| Entrez Gene | 51537 |
|---|
Application
Western blot analysis of MTP18 expression in non-transfected: (A) and mouse MTP18 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of MTP18 expression in non-transfected: (A) and mouse MTP18 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of MTP18 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with MTP also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
