Application
Western blot analysis of LASS3 expression in HeLa nuclear extract.Application
Western blot analysis of LASS3 expression in human fetal liver tissue extract.Application
Western blot analysis of LASS3 expression in Jurkat nuclear extract.| Product Name | LASS3 Antibody (O-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of LASS3 of human origin by WB, IP and ELISA |
| Modification Notes | The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in the production of a 419 amino acid protein (LASS3-long). LASS3 overproduction raises the level of several ceramide species, including C18:0- and C24:0-ceramides. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of LASS3 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of LASS3 of human origin by WB, IP and ELISA |
| Entrez Gene | 204219 |
|---|
Application
Western blot analysis of LASS3 expression in HeLa nuclear extract.
Application
Western blot analysis of LASS3 expression in human fetal liver tissue extract.
Application
Western blot analysis of LASS3 expression in Jurkat nuclear extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
