| Product Name | DSCR 10 Antibody (P-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of DSCR 10 of human origin |
| Modification Notes | An extra copy of chromosome 21, the smallest human autosome chromosome, results in Down syndrome. Down syndrome is a genetic disorder characterized by congenital heart abnormalities and mental retardation. The Down Syndrome Critical Region (DSCR) maps specifically to chromosme 21q22.2 and includes several genes which are likely associated with the pathogenesis of Down syndrome. Symptoms include abnormal neuronal differentiation and elevated apoptosis in the developing brain. DSCR 10 (Down syndrome critical region protein 10) is an 87 amino acid protein preferentially expressed in placenta and testis. The genes encoding DSCR 10 and DSCR 9 are not present in mice, suggesting that these genes have emerged during evolution in the primate lineage. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of DSCR 10 of human origin by WB, IF and ELISA non cross-reactive with other DSCR family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of DSCR 10 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of DSCR 10 of human origin |
| Application Notes | recommended for detection of DSCR 10 of human origin by WB, IF and ELISA non cross-reactive with other DSCR family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
