| Product Name | UBA3 Antibody (H-147) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 317-463 mapping at the C-terminus of UBA3 of human origin |
| Modification Notes | Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins (1-3). The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign and improperly folded proteins by targeting them for proteosome degradation (1-3). In the yeast, Saccharomyces cerevisiae, ubiquitin-like proteins include Rub1, Ula1, Uba3, Ubc12 and Ubc9 (4-5). Rub1 shares 53% homology with ubiquitin and requires activation via Ula1, Uba3 and Ubc12 in order to conjugate to substrates directed to different proteolytic systems (4). Skp1 connects cell cycle regulators to the ubiquitin proteolysis machinery (6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of UBA3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 317-463 mapping at the C-terminus of UBA3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 317-463 mapping at the C-terminus of UBA3 of human origin |
| Entrez Gene | 9039 |
|---|
| Application Notes | recommended for detection of UBA3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
