Application
Western blot analysis of RHBDL6 expression in CCRF-CEM whole cell lysate.| Product Name | RHBDL6 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a cytoplasmic domain of RHBDL6 of human origin |
| Modification Notes | Members of the rhomboid family of integral membrane proteins are related to Drosophila Rhomboid-1, a serine protease that cleaves the membrane domain of the Drosophila EGF-family protein, Spitz, to release a soluble growth factor. Rhomboid veinlet-like protein 6 (RHBDL6) is a 856 amino acid multi-pass endoplasmic reticulum membrane protein belonging to the rhomboid family. As an intramembrane protein, RHBDL6 has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. RHBDL6 may also indirectly activate the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration. RHBDL6 can exist as two isoforms due to alternative splicing events. RHBDL6 is encoded by a gene mapping to human chromosome 17p25.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RHBDL6 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with RHBDL1 or RHBDL2: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a cytoplasmic domain of RHBDL6 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a cytoplasmic domain of RHBDL6 of human origin |
| Entrez Gene | 79651 |
|---|
Application
Western blot analysis of RHBDL6 expression in CCRF-CEM whole cell lysate.| Application Notes | recommended for detection of RHBDL6 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with RHBDL1 or RHBDL2: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
