| Product Name | Eps8L3 Antibody (H-170) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-170 mapping at the N-terminus of Eps8L3 of human origin |
| Modification Notes | Eps8L3 (epidermal growth factor receptor kinase substrate 8-like protein 3), also known as EPS8R3, is a 593 amino acid protein that is related to Eps8, a novel EGF receptor substrate. Eps8L3 is a cytoplasmic protein that is part of a complex that contains Sos 1, Abi-1 and Eps8L2. Eps8L3 contains one SH3 domain, and has been found to interact with Abi-1 and FAS-L. Eps8L3 is expressed as three isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Eps8L3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-170 mapping at the N-terminus of Eps8L3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-170 mapping at the N-terminus of Eps8L3 of human origin |
| Entrez Gene | 79574 |
|---|
| Application Notes | recommended for detection of Eps8L3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
