epitope corresponding to amino acids 231-310 mapping near the C-terminus of Blr1 of human origin
Modification Notes
Burkitt’s lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G-protein coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer’s patch follicles. BLC expression in Peyer’s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Blr1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 231-310 mapping near the C-terminus of Blr1 of human origin
Tissue Specificity
epitope corresponding to amino acids 231-310 mapping near the C-terminus of Blr1 of human origin
recommended for detection of Blr1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.